The visceral antinociceptive mechanism of propofol may be in relation to opioid receptor at spinal level. 异丙酚抗内脏伤害作用机制可能与脊髓阿片受体有关。
In the present study, the common cellular mechanism of chronic visceral inflaming pain and morphine tolerance and the regulation of N methyl D aspartate ( NMDA) receptor were investigated. 因此探讨慢性内脏炎痛刺激及吗啡耐受间共同的细胞机理及N甲基D天冬氨酸(NMDA)受体相关的调节机理,为合理用药及药物开发提供实验依据。
Objective To investigate the relationship between visceral fat 、 first phase of insulin secretion and G-protein coupled receptor 40 expressing in beta cells in SD rats with different weight. 目的观察不同体重SD大鼠胰岛β细胞G蛋白偶联受体40(GPR40)表达水平与内脏脂肪含量及胰岛素1相分泌之间的关系。